Robert Rosen wrote extensively about many scientific subjects, with a research stream that always circled back to the essential question of 'What is life?' Below you can access most of his published work, as well as some unpublished notes, including the primary ideas that led to the development of Life Itself I: Epistemology, and its intended sequel, Life Itself II: Ontology.
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Natural systems are not Newtonian systems

Topics:

Dynamical Systems
Reductionism
Open Systems
Undated
Typed notes
Undated

Observation and biological systems

The paper proposes a general theory of observables in biological systems, emphasizing that understanding interactions requires aligning the observables used for system descriptions with those involved in the interactions

Topics:

Biological Systems
Observables
Measurement
Relational Biology
Reductionism
Dated
Article
1977

Old trends and new trends in general systems research

Ludwig von Bertalanffy and other systems theory pioneers were driven by biological challenges, highlighting biology's unique significance in science and suggesting that unresolved issues in this field will continue to influence systems research

Topics:

Systems Theory
von Bertalanffy
Reductionism
Empiricism
Machines
Dated
Article
1979

On a logical paradox implicit in the notion of a self-reproducing automation

An analysis of the formalization of von Neumann's automaton concept, highlighting a logical paradox in self-reproducing automata and its implications for biological problems

Topics:

Automata
von Neumann
Category Theory
Replication
(M,R)-Systems
Dated
Article
1959

On a unified approach to pattern generation

A discussion of the diverse biological contexts of pattern generation, highlighting the lack of a unified theory and proposing a novel mathematical approach through the concept of fiber spaces to better understand abstract patterns

Topics:

Patterns
Stability
Fibers
Morphogenesis
Dated
Commentary
1981
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