Robert Rosen wrote extensively about many scientific subjects, with a research stream that always circled back to the essential question of 'What is life?' Below you can access most of his published work, as well as some unpublished notes, including the primary ideas that led to the development of Life Itself I: Epistemology, and its intended sequel, Life Itself II: Ontology.
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Aging and the metrics of time

Age is an intrinsic measure of a system's state that can be derived from its dynamical equations, contrasting with clock time, and is influenced by the system's constitutive parameters and entropy production

Topics:

Time
Aging
Senescence
Thermodynamics
Dated
Article
1979

An approach to molecular similarity

Similarity is a fundamental concept that underpins various scientific disciplines and classification systems, particularly useful in biochemistry

Topics:

Similarity
Fractionability
Molecules
Chemistry
Dated
Chapter
1990

An example of two different primordials

Topics:

Graphs
Undated
Handwritten notes
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An hypothesis of Freese and the DNA-protein coding problem

Freese's Hypothesis posits that specific nucleotide alterations in DNA lead to distinct mutations, enabling the derivation of expressions for the smallest mutable DNA length and the maximum number of allelic molecules, with calculations revealing significant differences in data from bacteriophage and humans

Topics:

Genetics
Information
DNA
Dated
Article
1961

An idea which might have possibilities

Topics:

Stability
Dynamical Systems
Undated
Typed notes
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