Robert Rosen wrote extensively about many scientific subjects, with a research stream that always circled back to the essential question of 'What is life?' Below you can access most of his published work, as well as some unpublished notes, including the primary ideas that led to the development of Life Itself I: Epistemology, and its intended sequel, Life Itself II: Ontology.
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Phenotype cannot cause genotype

Topics:

Phenotype
Genotype
Causality
Undated
Typed notes
Undated

Planning, management, policies and strategies- Four fuzzy concepts

A discussion on the parallels between institutional planning for social systems and the anticipatory behavior of organisms, highlighting the lack of theoretical frameworks for such systems and the inevitable unforeseen consequences and complexities that arise from incomplete models

Topics:

Society
Anticipatory Systems
Side Effects
Dated
Article
1974

Protein folding- a prototype for control of complex systems

The study investigates how a limited set of control parameters can effectively manipulate a larger number of degrees of freedom in complex systems, specifically through an algorithm that predicts the three-dimensional structures of folded polypeptides from their amino acid sequences by establishing conditions for convergence to the correct structure

Topics:

Complexity
Control
Protein Folding
Dated
Article
1980

Recent developments in the theory of control and regulation of cellular processes

This article explores the theoretical foundations of regulation and control in cellular systems and their relevance for experimental biologists using model systems to study functional properties

Topics:

Control
Automata
Genetics
Feedback
Interaction
Dated
Chapter
1968

Relational biology and bionics

Relational Biology, as proposed by Rashevsky, emphasizes understanding biological systems through their functional components rather than structural ones, potentially enabling the engineering of analogs to real biological systems and enhancing both biological understanding and simulation techniques

Topics:

Relational Biology
Function
Simulation
Organization
Computability
Dated
Article
1963
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