Robert Rosen wrote extensively about many scientific subjects, with a research stream that always circled back to the essential question of 'What is life?' Below you can access most of his published work, as well as some unpublished notes, including the primary ideas that led to the development of Life Itself I: Epistemology, and its intended sequel, Life Itself II: Ontology.
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A relational theory of biological systems II

The study applies Category Theory to define and analyze abstract (M,R)-systems, introducing a time-lag structure that leads to a general Principle of Optimal Design and insights into the localization of repair mechanisms akin to cellular nuclear arrangements

Topics:

Category Theory
(M,R)-Systems
Relational Biology
Dated
Article
1959

A relational theory of the structural changes induced in biological systems by alterations in environment

Environmental changes can lead to diverse structural alterations in the metabolic and genetic systems of (M,R)-systems, with implications for understanding biological processes like the mitotic cycle

Topics:

(M,R)-Systems
Genetics
Metabolism
Dated
Article
1961

Are the dynamics of a system operationally determinable?

Proposal on how to empirically identify the rates of change of state variables in a dynamical system by observing its observables through measurement techniques

Topics:

Dynamical Systems
Measurement
Observables
Empiricism
Dated
Article
1972

A set is defined through the properties of the elements

Topics:

Set Theory
Syntax
Semantics
Undated
Typed notes
Undated

As I said, wow 21JUL1993

Topics:

Graphs
Emergence
(M,R)-Systems
Dated
Typed notes
1993
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